What is Aclasta®?

Aclasta® contains zoledronic acid (sometimes known as zoledronate). It belongs to a group of medicines called bisphosphonates. Zoledronic acid inhibits the release of calcium from bones. Aclasta® Medicine is commonly used to treat Paget's disease and osteoporosis in postmenopausal women. Aclasta® may also be used for other purposes not listed in this medication guide.

What is Aclasta® Used For?

Aclasta® is a substance that is used to treat a variety of conditions. Aclasta® is a drug that is used to Treat Osteoporosis (a disease that causes bones to become brittle) in both men and women after menopause. It's used in individuals who are at risk of fractures (broken bones), such as those who have recently broken their hip in a small trauma like a fall, and those whose osteoporosis is connected to long-term glucocorticoid Aclasta® Medication (a type of steroid). Adults with Paget's disease of the bones are treated with Aclasta®. The natural process of bone development is disrupted with this condition. Only with a prescription may the drug be obtained.

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What is the Function of Aclasta®?

When not enough new bone grows to replace the bone that is normally broken down, osteoporosis develops. The bones become thinner and weaker over time, making them more likely to shatter. Osteoporosis is more common in women after menopause when estrogen levels in the body drop. As a Side Effect of Glucocorticoid Therapy, osteoporosis can develop in both men and women. The bone breaks down more quickly in Paget's disease, and when it grows back, it is weaker than normal. Aclasta®'s active ingredient, zoledronic acid, is bisphosphonate. Aclasta® Medicine inhibits the activity of osteoclasts, which are cells in the body that tear down bone tissue.

How is Aclasta® Administered?

Aclasta® is administered by injecting it into a vein with a needle. This Aclasta® Injection will be given to you in a clinic or hospital environment. The medicine must be administered slowly by an IV infusion, which might take up to 15 minutes. Aclasta® is given only once a year in some cases. Pay attention to your doctor's directions. To avoid being dehydrated, drink at least 2 glasses of water within a few hours following your injection. While being treated with Aclasta®, your doctor may advise you to take calcium and/or vitamin D supplements. Follow your doctor's directions regarding the type and strength of calcium you should take. Your blood will need to be checked on a regular basis to ensure Aclasta® is improving your condition and not producing serious side effects. It's possible that your renal function will need to be checked as well. It's critical that you don't skip any of your doctor's appointments.

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Side Effects of Aclasta®:

Common side effects of Aclasta® include but are not limited to serious side effects:

  • Urinating less than usual or not at all.
  • Muscle spasms, numb or tingly feeling (especially around your mouth).
  • Fever, chills, body aches, flu symptoms.
  • Pale skin, easy bruising, unusual weakness.
  • Severe joint, bone, or muscle pain.

Less Serious Aclasta® Side Effects May Include:

  • Cough.
  • Loss of appetite, nausea, vomiting.
  • Diarrhea, constipation.
  • Headache, dizziness, tired feeling.
  • Low blood pressure, swelling in your legs or feet.
  • Bone, joint, or muscle pain.
  • Redness or swelling where the needle was placed.

Cautions To Take Aclasta®:

You will have to be careful regarding using Aclasta®. Here are some of the conditions to get cautions to take Aclasta®:

  • There is evidence that long-term use of this class of medication may contribute to a type of rare fracture of the long bone in the thigh of any form of injury.
  • People with cancer who are being treated with Aclasta® have a higher risk of developing osteonecrosis of the jaw.
  • If you experience changes to your vision, red eyes, or eye pain, contact your doctor as soon as possible.
  • If you have kidney disease or have a history of kidney disease, let your doctor know about these conditions before starting Aclasta®.

Frequently Asked Question

1. How does Aclasta® work?

Aclasta® is used to treat and prevent osteoporosis in postmenopausal women and prevent osteoporosis caused by steroid medications.

2. How should I use Aclasta®?

Aclasta® is used for Paget's disease and for the prevention of osteoporosis in postmenopausal women. It is also used for the treatment of osteoporosis in men, and for the treatment and prevention of osteoporosis caused by steroid medications.

3. Who should not take Aclasta®?

Do not use Aclasta® if you:

  • Are allergic to zoledronic acid or any ingredient of this medication.
  • Are allergic to any other bisphosphonate medication.
  • Pregnant or breastfeeding.
  • Have severely decreased kidney function.
  • Have low blood calcium levels.
4. How is Aclast given?

Aclasta® is given as an injection through a needle placed into a vein under the supervision of a specialist and professional doctor.

5. What happens if I overdose?

You should seek emergency medical attention if you think you have received too much Aclasta®. Overdose symptoms may include numbness or tingling in your hands and feet, muscle stiffness, spasms in the muscles of your face, uneven heartbeats, and wheezing or trouble breathing.